Product Details
Provide efficient custom virus vector services, supporting insertion of up to 4 genes, with viral titers reaching above 10^8 PFU/mL.
(Schematic diagram of SeV-F gene deletion)
| Lenti | AAV | ADV | SeV | ||
Virus type | dsRNA | ssDNA | dsDNA | ssRNA | |
| Packaging capacity | <7kb | <5kb | <7kb | <5 kb, no insert required | |
| envelope | Yes | None | None | Yes | |
| Particle diameter | 90-100nm | 20-30nm | 60-90nm | 150-200nm | |
| Onset time of expression | 48-72h | 72-96h | 24-48h | 48-72h | |
| Duration of expression | >6mths | >6mths | ~1mth | ~1mth | |
| Integration method | Random high-frequency integration | Targeted low-frequency integration | Targeted low-frequency integration | Non-integrating cytoplasmic expression | |
| Tropism | Broad host range | Broad host range | Broad host range | Broad host range | |
| Immunogenicity | Low | Low | High | High | |
| Exogenous gene expression efficiency | Moderate | Moderate | Moderate | High | |
| MOl | 5-100 | Above 100 | Above 10 | 3 | |
Comparison of biological characteristics of various viruses
F gene-deleted Sendai virus envelope
| Product Item Number | Service Name | delivery time | viral titer |
| SEV1001 | Custom packaging service for F gene-deleted Sendai virus | 90–120 days | >1×10^8 PFU/mL |
Custom Service Process
Viral vector construction and reverse genetics operations based on customer requirements;
Integration of gene viral vector construction with core patented technologies for cell line development;
Virus purification, titer determination, and gene expression validation.
Customer must provide
The gene plasmids required for the custom service (including gene sequencing data);
Alternatively, the GeneBank ID can be provided by us, but the customer must provide the corresponding gene information.